Article: Embryonic stem cells
April 28, 2011
This extract from the independent discusses a recent ruling that patents on embryonic stem cell research are immoral and illegal.
Uses for stem cell therapy
Blindness British scientists are hoping to begin clinical trials using stem cells that can develop into the light-sensitive cells at the back of the eye, which degrade in age-related macular degeneration. Scientists in the US are closer to using the cells to treat another form of blindness, Stargardt’s Macular Dystrophy.
Spinal cord injury American biotechnology company Geron has begun the first clincial trial of human embryonic stem cells to treat spinal injury. The cells will be injected into patients’ spinal cords, hopefully to restore lost nerve function.
Parkinson’s disease Scientists hope to develop a laboratory model of certain diseases, such as Parkinson’s, using stem cells derived from patients with the condition. In this way, they hope to create laboratory “models” of the disease based on human cells, which can be used for testing new drugs and treatments.
Heart disease Ultimately, the aim of stem cell therapy is to be able to mend damaged tissues in situ, rather than replacing a whole organ. Heart disease, for instance, could be tackled by injecting stem cells into the damaged site and allowing them to re-populate the damaged area of the organ. This would in theory be safer, cheaper and easier than carrying out a whole-organ transplant operation.
Steve Connor
Q&A: How this law could block the work of scientists
Q. What are embryonic stem cells?
These are cells derived from a very early human embryo, usually only three or four days after conception by IVF. They can be coaxed in the laboratory to develop into any of the cells found in the human body. Scientists hope to use them in revolutionary techniques, such as for testing new drugs or for transplant operations to replace damaged tissue.
Q. Why do scientists need to patent these inventions?
In order to encourage pharmaceutical companies to spend the millions of pounds necessary to develop a university project into a safe clinical technique, scientists need to ensure their intellectual property is protected.
Q. Why is this suddenly an issue?
It began with a court case in Germany when Greenpeace sued a Bonn University scientist, Oliver Brüstle, who held a patent on a technique involving embryonic stem cells. The court case went against Dr Brüstle and he appealed to a higher court, which referred it to the European Court of Justice, which asked its advocate general, Yves Bot, for his legal opinion on whether such patents should be allowed. M. Bot has just given his opinion, saying that patents involving human embryonic stem cells should be banned.
Q. Does this legal opinion matter?
The 13 judges of the Grand Chamber of the European Court will now consider their advocate general’s opinion. If they uphold it, all existing patents will be dissolved if they involve human embryonic stem cells. Scientists said this would be disastrous for the fledgling stem-cell industry because drug companies would flee to other countries where their intellectual property can be protected in law.
Q. Can’t the UK just ignore the European Court?
No, the decision of the court is binding on member states.
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